Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 2.871


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1



Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_21361901 5.034 MKRN3
makorin ring finger protein 3
chr10_-_11976704 3.407 LOC219731
hypothetical LOC219731
chr12_-_53153613 3.291 GTSF1
gametocyte specific factor 1
chr7_+_50318801 3.150 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr12_-_53153639 3.109 NM_144594
GTSF1
gametocyte specific factor 1
chrX_-_153632355 2.894 NM_001081573
NM_080612
GAB3

GRB2-associated binding protein 3

chrX_-_153428621 2.819 G6PD
glucose-6-phosphate dehydrogenase
chr10_-_43212681 2.777 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr6_-_168219380 2.767 NM_001122841
FRMD1
FERM domain containing 1
chr2_+_113648036 2.703 PSD4
pleckstrin and Sec7 domain containing 4
chr2_+_169367345 2.636 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chr1_+_38046005 2.579 C1orf122
chromosome 1 open reading frame 122
chr1_+_38046055 2.463 NM_001142726
NM_198446
C1orf122

chromosome 1 open reading frame 122

chrX_-_153428968 2.463 NM_001042351
G6PD
glucose-6-phosphate dehydrogenase
chr9_-_122595475 2.438 NM_012164
FBXW2
F-box and WD repeat domain containing 2
chr1_-_38046270 2.422 YRDC
yrdC domain containing (E. coli)
chrX_+_153429022 2.392 IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chrX_-_153908408 2.374 F8
coagulation factor VIII, procoagulant component
chrX_+_153428755 2.363 NM_001099857
NM_001145255
IKBKG

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

chrX_+_153908426 2.361 FUNDC2
FUN14 domain containing 2
chrX_+_153429042 2.285 IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr9_-_122595349 2.274 FBXW2
F-box and WD repeat domain containing 2
chrX_-_130792297 2.267 LOC286467
hypothetical LOC286467
chr1_+_20385164 2.264 NM_152376
UBXN10
UBX domain protein 10
chr19_+_17723285 2.246 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr2_+_113648020 2.246 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr1_-_38046433 2.151 YRDC
yrdC domain containing (E. coli)
chr7_+_106292932 2.134 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_120416680 2.080 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr10_-_43212703 2.071 NM_001098207
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chrX_+_150316351 2.035 VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr1_+_220953278 2.021 BROX
BRO1 domain and CAAX motif containing
chr6_-_31728447 2.019 NM_004639
NM_080702
NM_080703
BAG6


BCL2-associated athanogene 6


chr1_+_38046073 2.003 C1orf122
chromosome 1 open reading frame 122
chr1_-_38046410 2.001 YRDC
yrdC domain containing (E. coli)
chr22_-_19543069 1.988 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr7_+_106293112 1.970 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chrX_+_150316313 1.957 NM_001017980
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chrX_+_153908257 1.939 NM_023934
FUNDC2
FUN14 domain containing 2
chr7_+_106292975 1.939 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr22_+_19191875 1.937 MED15
mediator complex subunit 15
chr9_-_122595413 1.922 FBXW2
F-box and WD repeat domain containing 2
chr16_+_29581783 1.920 NM_001030288
SPN
sialophorin
chr22_+_19191859 1.913 MED15
mediator complex subunit 15
chrX_-_153428196 1.910 G6PD
glucose-6-phosphate dehydrogenase
chr22_-_17798998 1.895 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr22_+_19191886 1.887 MED15
mediator complex subunit 15
chr22_+_19191884 1.886 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr22_+_19191898 1.885 MED15
mediator complex subunit 15
chr22_-_17799177 1.847 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr22_+_17799341 1.833 MRPL40
mitochondrial ribosomal protein L40
chr7_-_134506001 1.831 C7orf49
chromosome 7 open reading frame 49
chr21_+_45184394 1.818


chrX_-_131179598 1.809 NM_021183
RAP2C
RAP2C, member of RAS oncogene family
chrX_+_150316332 1.801 VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr1_+_38046404 1.800 C1orf122
chromosome 1 open reading frame 122
chr22_+_19543248 1.790 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chr7_-_134506012 1.789 C7orf49
chromosome 7 open reading frame 49
chr22_+_19543350 1.780 SNAP29
synaptosomal-associated protein, 29kDa
chr16_+_29582065 1.748 SPN
sialophorin
chr9_-_37775013 1.747 EXOSC3
exosome component 3
chr16_+_29582069 1.736 NM_003123
SPN
sialophorin
chr1_-_51198383 1.712 FAF1
Fas (TNFRSF6) associated factor 1
chr22_-_17799215 1.711 NM_003325
HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr7_-_128482059 1.710 TNPO3
transportin 3
chr1_-_184610796 1.709 TPR
translocated promoter region (to activated MET oncogene)
chr7_-_134505923 1.704 C7orf49
chromosome 7 open reading frame 49
chr1_-_51198417 1.701 FAF1
Fas (TNFRSF6) associated factor 1
chr1_-_164004611 1.677 TMCO1
transmembrane and coiled-coil domains 1
chrX_-_131178977 1.665 RAP2C
RAP2C, member of RAS oncogene family
chr1_-_164004730 1.662 NM_019026
TMCO1
transmembrane and coiled-coil domains 1
chr22_-_18484428 1.662 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr22_-_19543099 1.661 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr2_+_74007439 1.659 NM_080916
NM_080918
DGUOK

deoxyguanosine kinase

chr1_-_40496161 1.631


chr22_+_19191964 1.630 MED15
mediator complex subunit 15
chr2_+_74007495 1.624 DGUOK
deoxyguanosine kinase
chr12_-_70343656 1.618


chr2_-_55131202 1.616 NM_020532
NM_153828
NM_207520
RTN4


reticulon 4


chr1_-_201194040 1.611 ADIPOR1
adiponectin receptor 1
chr17_+_72827185 1.609 NM_006640
SEPT9
septin 9
chr3_-_197549588 1.602 TM4SF19
transmembrane 4 L six family member 19
chr22_-_19543012 1.591 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr1_+_164004789 1.588 LOC100147773
hypothetical LOC100147773
chr6_-_31728405 1.585 BAG6
BCL2-associated athanogene 6
chr1_+_244796441 1.578 CNST
consortin, connexin sorting protein
chr3_-_197549640 1.571 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr22_+_20350272 1.568 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr17_+_46585928 1.563 NME1
non-metastatic cells 1, protein (NM23A) expressed in
chr19_+_40431618 1.562 LSR
lipolysis stimulated lipoprotein receptor
chrX_-_119578899 1.560 CUL4B
cullin 4B
chr9_-_37775064 1.550 NM_016042
NM_001002269
EXOSC3

exosome component 3

chr22_+_18485095 1.547 RANBP1
RAN binding protein 1
chr6_-_31728418 1.542 BAG6
BCL2-associated athanogene 6
chr9_-_37775052 1.541 EXOSC3
exosome component 3
chr2_+_74007523 1.537 DGUOK
deoxyguanosine kinase
chr3_+_151747204 1.537 NM_032025
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr19_+_40431678 1.534 LSR
lipolysis stimulated lipoprotein receptor
chr1_-_201193892 1.527 ADIPOR1
adiponectin receptor 1
chr6_+_160068531 1.521 WTAP
Wilms tumor 1 associated protein
chr11_+_384238 1.515 PKP3
plakophilin 3
chr17_+_46585895 1.511 NM_000269
NM_198175
NM_001018136
NME1

NME1-NME2
non-metastatic cells 1, protein (NM23A) expressed in

NME1-NME2 readthrough
chr1_-_38046439 1.503 NM_024640
YRDC
yrdC domain containing (E. coli)
chr15_-_62242352 1.502 NM_000942
PPIB
peptidylprolyl isomerase B (cyclophilin B)
chr17_+_24013320 1.501 SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chr6_-_28475478 1.497 NM_001163391
ZSCAN12
zinc finger and SCAN domain containing 12
chr9_-_37774785 1.496 EXOSC3
exosome component 3
chr9_-_130124820 1.485 TRUB2
TruB pseudouridine (psi) synthase homolog 2 (E. coli)
chr22_-_20235372 1.485 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr9_+_130124873 1.484 COQ4
coenzyme Q4 homolog (S. cerevisiae)
chr3_-_187025501 1.482 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr1_-_184610953 1.477 TPR
translocated promoter region (to activated MET oncogene)
chr21_-_37561463 1.447 DSCR3
Down syndrome critical region gene 3
chr6_-_31728363 1.443 BAG6
BCL2-associated athanogene 6
chr7_-_99355085 1.443 NM_033017
NM_033091
TRIM4

tripartite motif containing 4

chr15_-_72922533 1.436 ULK3
unc-51-like kinase 3 (C. elegans)
chr11_+_60954096 1.435 SDHAF2
succinate dehydrogenase complex assembly factor 2
chr7_-_128482354 1.429 TNPO3
transportin 3
chr6_-_36950520 1.409 PPIL1
peptidylprolyl isomerase (cyclophilin)-like 1
chr21_-_37561495 1.401 NM_006052
DSCR3
Down syndrome critical region gene 3
chr1_+_220953351 1.399 BROX
BRO1 domain and CAAX motif containing
chr2_-_55130963 1.398 RTN4
reticulon 4
chr14_-_37133927 1.381 FOXA1
forkhead box A1
chr6_+_160068553 1.380 WTAP
Wilms tumor 1 associated protein
chr11_-_66925875 1.379 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr2_+_174968751 1.377 SCRN3
secernin 3
chr6_+_160068544 1.368 WTAP
Wilms tumor 1 associated protein
chr15_-_72922577 1.365 NM_001099436
ULK3
unc-51-like kinase 3 (C. elegans)
chr6_+_31623370 1.360 NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr22_-_17846621 1.359 UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr17_+_72827654 1.357 SEPT9
septin 9
chr17_+_46585953 1.353 NME1
NME1-NME2
non-metastatic cells 1, protein (NM23A) expressed in
NME1-NME2 readthrough
chr14_-_37134050 1.353 FOXA1
forkhead box A1
chr1_+_244796426 1.349 CNST
consortin, connexin sorting protein
chr3_+_151747266 1.348 EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr6_+_160068598 1.348 NM_152857
WTAP
Wilms tumor 1 associated protein
chr6_+_31741814 1.348 CSNK2B
casein kinase 2, beta polypeptide
chr7_-_91713044 1.345 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr1_-_201194044 1.345 ADIPOR1
adiponectin receptor 1
chr13_-_45654296 1.344 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_33347833 1.340 RPS18
ribosomal protein S18
chr11_+_384199 1.338 NM_007183
PKP3
plakophilin 3
chr21_+_45184324 1.337 NM_058190
C21orf70
chromosome 21 open reading frame 70
chrX_-_153428258 1.336 NM_000402
G6PD
glucose-6-phosphate dehydrogenase
chr1_+_36169260 1.335 NM_024852
NM_177422
EIF2C3

eukaryotic translation initiation factor 2C, 3

chrX_-_40479893 1.331 MED14
mediator complex subunit 14
chr1_-_203867402 1.329 ELK4
ELK4, ETS-domain protein (SRF accessory protein 1)
chr8_-_104496444 1.326 SLC25A32
solute carrier family 25, member 32
chr22_+_18484810 1.325 NM_002882
RANBP1
RAN binding protein 1
chr9_-_133141726 1.325 NM_033387
FAM78A
family with sequence similarity 78, member A
chr8_-_104496495 1.322 SLC25A32
solute carrier family 25, member 32
chr3_-_187025438 1.320 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr11_+_60954150 1.318 NM_017841
SDHAF2
succinate dehydrogenase complex assembly factor 2
chrX_+_131179886 1.317


chr11_+_117735530 1.313 UBE4A
ubiquitination factor E4A (UFD2 homolog, yeast)
chr2_+_68855436 1.313 NM_001166276
NM_014882
ARHGAP25

Rho GTPase activating protein 25

chr16_-_1999760 1.307 NM_178167
ZNF598
zinc finger protein 598
chr3_-_47798372 1.305 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr11_+_117735502 1.303 NM_004788
UBE4A
ubiquitination factor E4A (UFD2 homolog, yeast)
chrX_+_119622012 1.303 MCTS1
malignant T cell amplified sequence 1
chr8_-_68136881 1.300 COPS5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
chr15_-_72922482 1.297 ULK3
unc-51-like kinase 3 (C. elegans)
chr7_-_99355065 1.293 TRIM4
tripartite motif containing 4
chr20_+_30019465 1.293 NM_001011718
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr2_-_136459507 1.290 DARS
aspartyl-tRNA synthetase
chr22_-_17846711 1.280 UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr11_+_125644232 1.279 FOXRED1
FAD-dependent oxidoreductase domain containing 1
chr2_+_174968701 1.276 NM_001193528
NM_024583
SCRN3

secernin 3

chr1_-_220829704 1.274 NM_005681
NM_139352
TAF1A

TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa

chr19_+_7608010 1.273 STXBP2
syntaxin binding protein 2
chr6_+_160068475 1.273 WTAP
Wilms tumor 1 associated protein
chr7_-_107997132 1.273 NM_182529
NM_001130475
THAP5

THAP domain containing 5

chr1_+_108904191 1.269 FAM102B
family with sequence similarity 102, member B
chr6_+_31623331 1.263 NM_001144961
NM_005007
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr6_-_33347563 1.261 NM_022553
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr7_-_128482417 1.255 NM_001191028
NM_012470
TNPO3

transportin 3

chr1_-_201194033 1.252 ADIPOR1
adiponectin receptor 1
chr1_-_20860610 1.249 NM_005216
DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr9_-_139043035 1.248 NM_212533
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr2_-_174968595 1.248 NM_004882
CIR1
corepressor interacting with RBPJ, 1
chr1_-_201194083 1.246 NM_015999
ADIPOR1
adiponectin receptor 1
chr5_+_149360503 1.244 HMGXB3
HMG box domain containing 3
chr3_-_151746970 1.243 NM_014445
SERP1
stress-associated endoplasmic reticulum protein 1
chr9_+_130124566 1.229 NM_016035
COQ4
coenzyme Q4 homolog (S. cerevisiae)
chr6_-_31728121 1.226 NM_001098534
BAG6
BCL2-associated athanogene 6
chr1_-_165754325 1.223 NM_000734
NM_198053
CD247

CD247 molecule

chrX_+_133952633 1.220 NM_001163438
LOC644538
hypothetical protein LOC644538
chr7_-_99355051 1.217 TRIM4
tripartite motif containing 4
chr11_+_117735529 1.217 UBE4A
ubiquitination factor E4A (UFD2 homolog, yeast)
chr1_+_40278958 1.215 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr6_-_36950729 1.214 PPIL1
peptidylprolyl isomerase (cyclophilin)-like 1
chr5_-_40871040 1.212 RPL37
SNORD72
ribosomal protein L37
small nucleolar RNA, C/D box 72
chr22_+_21852911 1.212 BCR
breakpoint cluster region
chrX_-_119578747 1.211 NM_001079872
CUL4B
cullin 4B
chr3_+_47004457 1.209 NBEAL2
neurobeachin-like 2
chr20_+_60246971 1.208 OSBPL2
oxysterol binding protein-like 2
chr12_-_104153920 1.203 NM_018171
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr6_-_153365532 1.198 MTRF1L
mitochondrial translational release factor 1-like
chr1_+_167604056 1.194 BLZF1
basic leucine zipper nuclear factor 1
chr5_+_149360361 1.190 NM_014983
HMGXB3
HMG box domain containing 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.41 8.83e-45 GO:0044260 cellular macromolecule metabolic process
1.34 5.64e-36 GO:0043170 macromolecule metabolic process
1.53 2.48e-31 GO:0090304 nucleic acid metabolic process
1.46 7.79e-31 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 9.74e-27 GO:0044237 cellular metabolic process
1.54 7.22e-24 GO:0016070 RNA metabolic process
1.50 2.61e-22 GO:0010467 gene expression
1.22 7.52e-22 GO:0044238 primary metabolic process
1.35 1.10e-20 GO:0034641 cellular nitrogen compound metabolic process
1.40 9.65e-20 GO:0044267 cellular protein metabolic process
1.33 1.51e-19 GO:0006807 nitrogen compound metabolic process
1.19 1.64e-19 GO:0008152 metabolic process
1.47 1.65e-17 GO:0009059 macromolecule biosynthetic process
1.79 4.73e-17 GO:0006396 RNA processing
1.47 6.76e-17 GO:0034645 cellular macromolecule biosynthetic process
1.86 1.02e-16 GO:0016071 mRNA metabolic process
2.41 5.06e-16 GO:0000375 RNA splicing, via transesterification reactions
1.34 1.00e-15 GO:0071841 cellular component organization or biogenesis at cellular level
1.29 1.74e-15 GO:0071840 cellular component organization or biogenesis
2.39 2.88e-15 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.39 2.88e-15 GO:0000398 nuclear mRNA splicing, via spliceosome
1.92 3.19e-14 GO:0016032 viral reproduction
2.05 1.47e-13 GO:0008380 RNA splicing
1.92 3.32e-13 GO:0006397 mRNA processing
1.10 7.22e-13 GO:0009987 cellular process
1.77 1.31e-12 GO:0006974 response to DNA damage stimulus
1.29 3.17e-12 GO:0019538 protein metabolic process
1.26 2.96e-11 GO:0016043 cellular component organization
1.30 5.37e-11 GO:0071842 cellular component organization at cellular level
1.56 7.46e-11 GO:0033554 cellular response to stress
1.71 7.87e-11 GO:0044265 cellular macromolecule catabolic process
1.31 8.59e-11 GO:0044249 cellular biosynthetic process
1.54 1.17e-10 GO:0045184 establishment of protein localization
1.65 1.91e-10 GO:0009057 macromolecule catabolic process
2.16 2.42e-10 GO:0022613 ribonucleoprotein complex biogenesis
1.54 2.68e-10 GO:0015031 protein transport
2.10 9.37e-10 GO:0071843 cellular component biogenesis at cellular level
1.46 1.66e-09 GO:0008104 protein localization
1.36 2.13e-09 GO:0006996 organelle organization
1.64 2.14e-09 GO:0000278 mitotic cell cycle
1.28 2.83e-09 GO:0009058 biosynthetic process
1.39 1.85e-08 GO:0033036 macromolecule localization
1.44 3.41e-08 GO:0007049 cell cycle
1.41 3.51e-08 GO:0044248 cellular catabolic process
1.51 4.26e-08 GO:0046907 intracellular transport
1.83 4.81e-08 GO:0051329 interphase of mitotic cell cycle
1.54 7.05e-08 GO:0022403 cell cycle phase
1.82 7.13e-08 GO:0051325 interphase
1.95 1.20e-07 GO:0071156 regulation of cell cycle arrest
1.76 2.12e-07 GO:0006281 DNA repair
1.96 2.13e-07 GO:0000075 cell cycle checkpoint
1.73 2.26e-07 GO:0030163 protein catabolic process
1.77 2.42e-07 GO:0051603 proteolysis involved in cellular protein catabolic process
1.56 4.20e-07 GO:0006259 DNA metabolic process
1.75 4.29e-07 GO:0044257 cellular protein catabolic process
1.84 4.62e-07 GO:0034660 ncRNA metabolic process
1.47 5.18e-07 GO:0022402 cell cycle process
1.77 5.60e-07 GO:0006511 ubiquitin-dependent protein catabolic process
1.29 6.88e-07 GO:0043412 macromolecule modification
1.76 6.99e-07 GO:0043632 modification-dependent macromolecule catabolic process
1.73 8.19e-07 GO:0010564 regulation of cell cycle process
1.75 9.93e-07 GO:0019941 modification-dependent protein catabolic process
2.57 1.82e-06 GO:0006353 transcription termination, DNA-dependent
1.29 2.10e-06 GO:0006464 protein modification process
1.75 2.55e-06 GO:0006412 translation
2.19 2.83e-06 GO:0042254 ribosome biogenesis
1.41 3.23e-06 GO:0032774 RNA biosynthetic process
1.35 5.95e-06 GO:0051641 cellular localization
1.32 6.63e-06 GO:0009056 catabolic process
1.35 1.15e-05 GO:0044085 cellular component biogenesis
1.36 1.70e-05 GO:0051649 establishment of localization in cell
1.41 4.36e-05 GO:0043933 macromolecular complex subunit organization
2.16 5.14e-05 GO:0000084 S phase of mitotic cell cycle
1.54 5.66e-05 GO:0034621 cellular macromolecular complex subunit organization
2.12 1.07e-04 GO:0051320 S phase
1.64 1.19e-04 GO:0070647 protein modification by small protein conjugation or removal
1.72 1.40e-04 GO:0016567 protein ubiquitination
1.71 1.49e-04 GO:0007346 regulation of mitotic cell cycle
1.78 2.42e-04 GO:0033365 protein localization to organelle
1.95 2.98e-04 GO:0000082 G1/S transition of mitotic cell cycle
1.68 3.03e-04 GO:0032446 protein modification by small protein conjugation
2.38 3.04e-04 GO:0006302 double-strand break repair
2.00 4.63e-04 GO:0007093 mitotic cell cycle checkpoint
2.38 4.65e-04 GO:0072594 establishment of protein localization to organelle
1.48 4.92e-04 GO:0070727 cellular macromolecule localization
1.56 5.15e-04 GO:0006886 intracellular protein transport
1.43 7.07e-04 GO:0051726 regulation of cell cycle
1.44 7.74e-04 GO:0071822 protein complex subunit organization
1.77 7.94e-04 GO:0006457 protein folding
1.80 8.89e-04 GO:0006260 DNA replication
1.47 9.71e-04 GO:0034613 cellular protein localization
2.16 1.02e-03 GO:0006364 rRNA processing
2.26 1.13e-03 GO:0006354 transcription elongation, DNA-dependent
1.78 1.28e-03 GO:0034470 ncRNA processing
2.72 1.38e-03 GO:0006369 termination of RNA polymerase II transcription
1.61 1.52e-03 GO:0048285 organelle fission
1.35 1.80e-03 GO:0006351 transcription, DNA-dependent
2.10 2.00e-03 GO:0016072 rRNA metabolic process
2.02 2.12e-03 GO:0000077 DNA damage checkpoint
1.61 2.24e-03 GO:0000280 nuclear division
1.61 2.24e-03 GO:0007067 mitosis
1.98 2.46e-03 GO:0031570 DNA integrity checkpoint
2.20 2.51e-03 GO:0000216 M/G1 transition of mitotic cell cycle
1.16 2.68e-03 GO:0060255 regulation of macromolecule metabolic process
1.69 3.22e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.45 4.18e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.58 4.79e-03 GO:0000087 M phase of mitotic cell cycle
1.79 6.77e-03 GO:0010498 proteasomal protein catabolic process
1.79 6.77e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.52 8.31e-03 GO:0051301 cell division
1.58 8.42e-03 GO:0006366 transcription from RNA polymerase II promoter
2.30 9.49e-03 GO:0006368 transcription elongation from RNA polymerase II promoter
2.07 1.02e-02 GO:0071826 ribonucleoprotein complex subunit organization
1.83 1.05e-02 GO:0006310 DNA recombination
2.09 1.09e-02 GO:2000045 regulation of G1/S transition of mitotic cell cycle
2.23 1.42e-02 GO:0071158 positive regulation of cell cycle arrest
1.76 1.56e-02 GO:0022415 viral reproductive process
2.10 1.75e-02 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.56 1.77e-02 GO:0006283 transcription-coupled nucleotide-excision repair
2.15 1.95e-02 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.17 2.04e-02 GO:0006289 nucleotide-excision repair
1.35 2.20e-02 GO:0065003 macromolecular complex assembly
2.08 2.48e-02 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.08 2.48e-02 GO:0051443 positive regulation of ubiquitin-protein ligase activity
2.08 2.48e-02 GO:0071779 G1/S transition checkpoint
1.14 2.51e-02 GO:0031323 regulation of cellular metabolic process
1.65 2.66e-02 GO:0006605 protein targeting
1.56 3.05e-02 GO:0010608 posttranscriptional regulation of gene expression
2.03 3.22e-02 GO:0051351 positive regulation of ligase activity
1.26 3.78e-02 GO:0010604 positive regulation of macromolecule metabolic process
2.09 3.99e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.28 4.03e-02 GO:0032268 regulation of cellular protein metabolic process
1.33 4.44e-02 GO:0016192 vesicle-mediated transport
1.69 4.58e-02 GO:0043687 post-translational protein modification
2.02 4.83e-02 GO:0022618 ribonucleoprotein complex assembly
2.02 4.83e-02 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.19 4.90e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.19 4.90e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
2.19 4.90e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.19 4.90e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.19 4.90e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.19 4.90e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
2.19 4.90e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.19 4.90e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
1.47 4.90e-02 GO:0016568 chromatin modification

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 2.53e-46 GO:0044424 intracellular part
1.16 6.05e-45 GO:0005622 intracellular
1.22 3.18e-42 GO:0043227 membrane-bounded organelle
1.22 5.78e-42 GO:0043231 intracellular membrane-bounded organelle
1.19 1.61e-39 GO:0043229 intracellular organelle
1.19 5.33e-39 GO:0043226 organelle
1.56 1.66e-36 GO:0044428 nuclear part
1.53 1.14e-34 GO:0031974 membrane-enclosed lumen
1.53 5.67e-34 GO:0070013 intracellular organelle lumen
1.29 1.47e-33 GO:0044446 intracellular organelle part
1.29 6.28e-33 GO:0044422 organelle part
1.51 1.26e-32 GO:0043233 organelle lumen
1.58 2.86e-32 GO:0031981 nuclear lumen
1.27 1.70e-29 GO:0005634 nucleus
1.99 3.64e-23 GO:0030529 ribonucleoprotein complex
1.17 6.39e-23 GO:0005737 cytoplasm
1.58 1.08e-21 GO:0005654 nucleoplasm
1.32 2.54e-21 GO:0032991 macromolecular complex
1.20 7.22e-18 GO:0044444 cytoplasmic part
1.76 3.47e-13 GO:0005730 nucleolus
1.35 5.78e-13 GO:0005829 cytosol
1.29 2.81e-12 GO:0043228 non-membrane-bounded organelle
1.29 2.81e-12 GO:0043232 intracellular non-membrane-bounded organelle
2.40 4.34e-11 GO:0005681 spliceosomal complex
1.24 1.78e-09 GO:0043234 protein complex
2.65 1.09e-08 GO:0071013 catalytic step 2 spliceosome
1.51 2.29e-08 GO:0044451 nucleoplasm part
1.04 2.24e-07 GO:0044464 cell part
1.04 2.40e-07 GO:0005623 cell
1.84 1.21e-06 GO:0016604 nuclear body
2.77 8.34e-05 GO:0015030 Cajal body
1.44 1.88e-04 GO:0005694 chromosome
2.09 7.62e-04 GO:0042470 melanosome
2.09 7.62e-04 GO:0048770 pigment granule
1.85 8.45e-04 GO:0000151 ubiquitin ligase complex
1.44 1.90e-03 GO:0044427 chromosomal part
3.05 2.77e-03 GO:0044452 nucleolar part
1.69 2.92e-03 GO:0005840 ribosome
1.19 4.17e-03 GO:0031090 organelle membrane
2.77 5.05e-03 GO:0030532 small nuclear ribonucleoprotein complex
1.23 9.92e-03 GO:0005739 mitochondrion
1.27 1.41e-02 GO:0005794 Golgi apparatus
1.76 2.87e-02 GO:0016607 nuclear speck
1.57 2.94e-02 GO:0000228 nuclear chromosome
1.70 2.99e-02 GO:0000793 condensed chromosome
1.33 4.99e-02 GO:0044431 Golgi apparatus part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 1.88e-30 GO:0005515 protein binding
1.10 2.19e-16 GO:0005488 binding
1.62 7.65e-15 GO:0003723 RNA binding
1.26 7.41e-13 GO:0003676 nucleic acid binding
1.29 8.23e-10 GO:0000166 nucleotide binding
1.28 5.04e-07 GO:0035639 purine ribonucleoside triphosphate binding
1.28 5.40e-07 GO:0017076 purine nucleotide binding
1.28 9.82e-07 GO:0032553 ribonucleotide binding
1.28 9.82e-07 GO:0032555 purine ribonucleotide binding
1.30 1.80e-06 GO:0030554 adenyl nucleotide binding
1.30 1.86e-06 GO:0032559 adenyl ribonucleotide binding
1.30 2.50e-06 GO:0005524 ATP binding
1.85 1.10e-04 GO:0008168 methyltransferase activity
1.12 1.43e-04 GO:0003824 catalytic activity
1.80 3.90e-04 GO:0016741 transferase activity, transferring one-carbon groups
1.50 2.11e-03 GO:0003712 transcription cofactor activity
1.49 2.44e-03 GO:0000988 protein binding transcription factor activity
1.49 2.44e-03 GO:0000989 transcription factor binding transcription factor activity
1.34 2.66e-03 GO:0016462 pyrophosphatase activity
1.34 3.19e-03 GO:0017111 nucleoside-triphosphatase activity
1.57 3.53e-03 GO:0042623 ATPase activity, coupled
1.33 3.58e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
2.23 3.87e-03 GO:0008094 DNA-dependent ATPase activity
1.44 3.96e-03 GO:0016874 ligase activity
1.33 4.80e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.21 4.95e-03 GO:0016740 transferase activity
1.59 8.36e-03 GO:0019787 small conjugating protein ligase activity
1.60 1.18e-02 GO:0004842 ubiquitin-protein ligase activity
2.00 1.81e-02 GO:0008135 translation factor activity, nucleic acid binding
1.41 2.51e-02 GO:0004674 protein serine/threonine kinase activity
1.49 2.90e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.30 3.20e-02 GO:0019899 enzyme binding
1.92 4.05e-02 GO:0008565 protein transporter activity
1.78 4.67e-02 GO:0051082 unfolded protein binding